Aggressive cancer phenotypes

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For instance, hair loss, which is one of the major concerns for some patients, such as a young lady with BM of breast cancer, is a less frequently encountered problem with SRS than WBRT as a result of the smaller irradiated field size and focalized dose distribution Figure 2. All the aforementioned advantages of SRS are provided by utilization of multiple convergent narrow beams to deliver high dose focal irradiation in a single fraction by using multiple cobalt sources, linear accelerators or cyclotrons 37, Similar with neurosurgery, SRS alone or in combination with WBRT has been exhibited to associate with prolonged overall survival, local control aggressive cancer phenotypes also better neurologic status in these patients compared to WBRT alone 33, However, SRS differs from neurosurgery by offering a chance of ablative treatment to those patients who are not appropriate candidates for neurosurgery due to various reasons.

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By gene expression analysis, an intrinsic heterogeneity was identified corresponding to different chemo sensitivity. A tendency towards aggressive adjuvant treatment is observable even though there are good prognostic histologies. We conducted a systematic review in order to identify the prognostic factors studied aggressive cancer phenotypes early stages of TNBC. Young age, metaplastic histology, peritumoral vascular invasion, high tumoral grade and high expression of Ki were consistently prognostic factors for early recurrence.

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Rezumat Tesutul osos reprezinta un micromediu hypoxic capabil sa potenteze metastazele tumorale si cresterea acestora. Aceasta lucrare este o trecere in revista a datelor din literatura privind mecanismele moleculare ale hipoxiei ca unul dintre contributorii majori ai metastazelor tumorale osoase, care regleaza produsii de secretie cu rol in influentarea proliferarii si a raspandirii celulelor tumorale. Cuvinte-cheie: hypoxia, remodelarea osoasa, metastaze tumorale Abstract Bone tissue is a hypoxic microenvironment capable of potentiating tumor metastasis and growth.

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Publicaţii laborator Abstract Aim: to describe two cases of familial papillary thyroid carcinoma. Material and methods: patients were investigated by fine needle biopsy, MRI imaging and tumor biopsy, first case and histological examination of familial cancer journal and thyroid tumors first case and histological examination of thyroid tumor second case. Results and discussion: case presentation: first case, 68 years old man had aggressive cancer phenotypes colonic polyposis attenuated form with only a few polyps and a thyroid nodule.

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Слова были странные окрашенные печалью. И ходить в непохожих -- тоже было и странно и грустно. Когда о нем так говорили -- а он частенько слышал, что о нем говорят именно так, когда полагают, что он не может услышать, aggressive cancer phenotypes да в словах этих звучал некий оттенок многозначительности и в нем содержалось нечто большее, нежели просто какая-то возможная угроза его личному счастью.

И названые родители, и его наставник Джизирак, и все, кого он знал, пытались уберечь его от тайной правды, словно бы хотели навсегда сохранить для него неведение долгого детства.