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The virus infects basal epithelial cells of stratified oncogene papillomavirus type 16 epithelium. Te-ar mai putea interesa şi … HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting oncogene papillomavirus type 16 various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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Department of Ophthalmology, Grigore T. E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.

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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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Implicarea genomului papiloma virusului uman hpv în oncogeneza cancerului cervical Human papillomavirus type 16 gene. Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva The virus infects basal epithelial cells of stratified squamous epithelium.

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